مشاريع التخرج - The role of intimin in adhesion of enteropathogenic Escherichia coli
عنوان المشروع | The role of intimin in adhesion of enteropathogenic Escherichia coli |
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المشرف على المشروع | م.د.مختار جواد كاظم |
العام الدراسي | 2020-2021 |
تقديم الطالب | 1- وداد عماد محمد |
و الطالب | سرى رياض خليل |
و الطالب | غسق محمد عبدالحسين |
ملخص | Enteropathogenic Escherichia coli (EPEC), an important paediatric diarrhoeal pathogen, employs multiple adhesins to colonize the small bowel and produces characteristic ‘attaching and effacing’ (A/E) lesions on small intestinal enterocytes. EPEC adhesins that have been associated with A/E adhesion and intestinal colonization include bundle-forming pili (BFP), intimin are involved in bacteria–bacteria interaction and microcolony formation but their role in cell adhesion remains unclear; intimin is the well characterized intimate EPEC adhesin which binds the translocated intimin receptor ( Tir). |